IVF treatment linked to higher risk of ovarian tumours

The helper is now the cuplrit?
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Posted: 27 October 2011


Expert performs in-vitro fertilization. (AFP/Saeed Khan)
PARIS: Women who were given hormone treatment for in-vitro fertilisation (IVF) ran twice the risk of ovarian malignancies compared with counterparts who did not undergo IVF, a study said on Thursday.

Doctors in the Netherlands compared the long-term health of more than 19,000 women who had received at least one IVF ovarian stimulation treatment with just over 6,000 similarly infertile counterparts who had not been treated for IVF.

Of the 25,000 women they studied, 77 developed ovarian malignancies in the ensuing 15 years, a risk that in absolute terms was very low.

But in relative terms, the numbers were much higher in the IVF group, which had 61 out of the 77 cases compared to 16 in the non-IVF group.

Thirty of the 61 were cases of invasive ovarian cancer, which usually requires extensive surgery and chemotherapy and has a low survival rate.

The other 31 cases were borderline ovarian tumours, which have low malignancy potential and are rarely fatal but require major surgery.

After taking into account the age and how many children (if any) the women had had, as well as other factors that could skew the results, the researchers found a two-fold increase in the risk of ovarian malignancies in the IVF group.

But the risk did not increase with more IVF cycles, a surprise finding that will be probed further.

The study, appearing in the European journal Human Reproduction, is based on data from national health registries and women diagnosed with subfertility problems at the Netherlands' 12 IVF clinics between 1980 and 1995.

-AFP/pn



Taken from ChannelNewsAsia.com; source article is below:
IVF treatment linked to higher risk of ovarian tumours

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'Drunkorexia' growing problem on campuses: Research

A wreath Kolsch Beer - LA Times of Kölsch.Image via WikipediaThe rare death of a university student from binge drinking has brought heightened attention to the issue.

By Jordan Press, Postmedia News

October 19, 2011


More students on university and college campuses are cutting calories during the day so they can binge drink at night, leaving them open to long-term health problems, new U.S. research suggests.

Results from a study out of the University of Missouri found that as many as one in five students save their calories for alcohol, an eating and drinking disorder dubbed 'drunkorexia.'

The findings, which have been presented publicly but not peer-reviewed, are part of a growing body of research showing drunkorexia as a trend on campuses.

Students in the study said their motivations to be drunkorexic included getting drunk faster, spending money on alcohol that might otherwise be spent on food, and keeping their weight down.

The growing problem is another issue counsellors will have to handle as students spend their limited funds in potentially unhealthy ways, said Dr. Valerie Taylor, chief of psychiatry at Women's College Hospital in Toronto.

"It's ironic. Society has to adapt to our changing environment and these kids are doing the same thing," Taylor said.

"Perhaps . . . because students don't have as much money, it's becoming more prevalent."

Taylor said alcohol abuse and mental-health issues are on the rise in Canada and schools continue to try to address the problem.

One example was in May when Queen's University in Kingston, Ont., said it would address a "culture of drinking on campus" after the release of a coroner's report that concluded excessive drinking was a factor in the deaths of two students at the beginning and end of the 2010 fall term.

"Like other universities, we are wrestling with the societal issue of alcohol consumption and excessive drinking in the university-aged population," the university's dean of student affairs, John Pierce, said in a statement at the time. "We've been proactively addressing this issue for several years and will continue to do so."

Drunkorexia differs from anorexia, where people purposely starve themselves to lose weight, Taylor said. It's also different from dieters who avoid alcohol to lose weight, but may give in and have a drink when their willpower fails them, she said.

The research suggests the majority of drunkorexics are women — they were three times more likely to have the disorder than men.

Women are at higher risk for health problems related to binge drinking because they metabolize alcohol faster than men. This means women can get sick faster and suffer damage to vital organs sooner than men.

"Women are bombarded with lots of images with what's socially acceptable," Taylor said. "They desperately want to not gain weight.

"If they can only consume so many calories a day . . . that's going to come from alcohol."

Drunkorexics are at greater risk of becoming sexual assault victims and suffering from substance abuse and more severe eating disorders later in life, Taylor said.

What these students may not be aware of is that drunkorexia could affect their ability to learn and to make decisions, and ultimately damage their internal organs, the Missouri study suggests.

jpress@postmedia.com
Twitter.com/jordan_press


Taken from MontrealGazette.com; source article is below:
'Drunkorexia' growing problem on campuses: Research

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Lifestyle changes may cut Alzheimer's risk, says study

On the other hand...
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Posted: 20 July 2011

(AFP/File/Sebastien Bozon)
PARIS: Up to half of worldwide cases of Alzheimer's disease could be due to modifiable lifestyle risk factors, according to a study released Tuesday based on a mathematical model.

The theoretical analysis suggests that seven known behaviour-related risk factors, taken together, account for 50 per cent of the more than 35 million cases of dementia worldwide.

The findings "suggest that relatively simple lifestyle changes such as increasing physical activity and quitting smoking could have a dramatic impact" on the number of Alzheimer's cases over time, said lead researcher Deborah Barnes, a professor at the University of California in San Francisco.

The study, presented at an international Alzheimer's conference in Paris, is among the first attempts to link risk factors with the degenerative brain disease, which causes memory loss, disability and eventually death.

Only a tiny percentage of cases -- about one per cent -- are clearly caused by genetic factors.

Otherwise, while the process by which the disease attacks nerve cells in the brain is well known, its origins remain poorly understood.

Barnes and colleagues used a statistical method to measure the percentage of cases which might be attributable, at least in part, to each of the risk factors assessed.

Worldwide, they found that a low level of education was linked to 19 per cent of cases, smoking to 14 per cent, physical inactivity to 13 per cent, depression to 11 per cent, mid life hypertension and obesity to five and two per cent, respectively, and diabetes to two per cent.

When combined, these seven modifiable risk factors contribute to as many as 17 million Alzheimer's cases worldwide, and about three million in the United States, the study found.

While eliminating harmful lifestyle habits entirely is likely to remain a theoretical exercise, the more realistic goal of reducing them by a quarter would cut the number of cases globally by three million, the researchers calculated.

"The next step is to perform large-scale studies with people to discover whether changing these lifestyle factors will actually lower Alzheimer's risk," Barnes said in a statement.

The number of people afflicted by Alzheimer's is expected to more than triple by 2050 as populations across the planet age.

The disease is characterised by unwanted proteins that form plaque in some areas of the brain, ultimately destroying neurons and leading to irreversible brain damage.

Typical symptoms are memory loss, erratic behaviour and extreme agitation.

Alzheimer's affects 13 per cent of people over 65, and up to 50 per cent of those over 85.

-AFP/ac



Taken from ChannelNewsAsia.com; source article is below:
Lifestyle changes may cut Alzheimer's risk, says study


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Head injuries in war, sports may boost dementia

Somehow, some memories would rather be forgotten by vets, don't you think? Or you also don't remember anything anymore?
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Posted: 19 July 2011

A doctor looks at several brain scans a hospital (AFP/File, Fethi Belaid)
PARIS - Brain injuries sustained on the battlefield and the gridiron of American football likely boost the risk of dementia later in life, according to two studies released Monday.

In a third study, also presented at an international Alzheimer's conference in Paris this week, researchers unveiled evidence that falling over in daily life may be an early warning sign of the onset of Alzheimer's.

Older war veterans who experienced traumatic brain injury face a doubled risk of developing dementia, according to a study led by Kristine Yaffe, head of the Memory Disorders Program at the San Francisco Veterans Association medical centre.

Reviewing the medical records of 281,540 US veterans aged 55 and older, they found that the risk of dementia was 15.3 percent in those who had had traumatic brain injuries (TBI) compared to 6.8 percent for ex-soldiers who had not.

"This issue is important, because TBI is very common," Yaffe said in a statement.

"About 1.7 million people experience a TBI each year in the United States, primarily due to falls and car crashes."


Brain injuries sustained on the battlefield and the gridiron of American football likely boost the risk of dementia (AFP/Getty Images/File, Spencer Platt)
Such injuries are also known as the "signature wound" of the conflicts in Afghanistan and Iraq, accounting for 22 percent of casualties overall and 59 percent of blast-related injuries.

The research suggests that the death and damage of axons -- long cell extensions that form connections among nerve cells in the brain -- may be to blame for the higher risk of dementia.

The swelling of the traumatised axons accompanies the accumulation of proteins called beta-amyloid, a hallmark of Alzheimer's.

Amyloid plaques similar to those found in the brains of people with Alzheimer's are present in up to 30 percent of TBI patients who do not survive their injuries, regardless of age.

In the second study, scientists led by Christopher Randolph of Loyola University Medical Center in Chicago compared the likelihood of decline in basic cognitive functions among retired football players and in older adults who had not played professional sports.

The repeated head-on clashes typical of American football may -- despite protective gear -- boost the chances of long-term brain damage.


Brain injuries sustained on the battlefield and the gridiron of American football likely boost the risk of dementia (AFP/File, Samuel Kubani)
Of more than 500 ex-football players, mean age 61, who responded to a health survey in 2008, just over 35 percent gave answers suggesting possible dementia, nearly triple the rate of Alzheimer's among Americans over 65.

Researchers followed up on this data to identify players with Mild Cognitive Disorder (MCI), often a precursor to full-blown dementia or Alzheimer's.

The study compared neurological and psychological test results from this group with two other groups, neither of which had played pro sports: demographically similar adults who showed no cognitive decline, and adults diagnosed with MCI.

The former athletes were clearly impaired compared to the normal adults. They were slightly less impaired that the non-athlete group diagnosed with MCI, but were considerably younger.

"It appears that there may be a very high rate of cognitive impairment in these retired football players compared to the general population," Randolph said, pointing to "repetitive head trauma" as the likely culprit.

In the last study, Washington University researcher Susan Stark and colleagues tracked 125 older adults over eight months, asking them to log any falls they made in day-to-day life.

Those adults with so-called preclinical Alzheimer's -- signs measurable in brain scans even in the absence of memory loss -- were nearly three times more likely to fall for each notch on a scale used to measure Alzheimer's progression.

"This study suggests that higher rates of falls can occur very early in the disease process," said Stark.

Traditional hallmarks of Alzheimer's such as memory loss remain critically important, said Maria Carrillo, a senior director at the Alzheimer's Association in the United States, commenting on the study.

"But these results also illustrate the significance of understanding that, in some people, changes in gait and balance may appear before cognitive impairment," she said.

-AFP/rt



Taken from ChannelNewsAsia.com; source article is below:
Head injuries in war, sports may boost dementia


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Tai chi improves balance, mental health in elderly: study

Growing old has help in many ways, after all...
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Posted: 17 May 2011

A student (C) learns the moves of Tai Chi from his master (R).
PARIS - A review of medical studies gave the thumbs-up on Monday to tai chi as a way of preventing falls and improving mental health in the elderly, but does not confirm other claims made for the Chinese martial art.

British and South Korean researchers looked at 35 assessments of tai chi found in English-language, Chinese and Korean databases.

There was "convincingly positive" evidence that, among the elderly, practicising tai chi helped sense of balance and boosted psychological wellbeing.

However, the sport "seems to be ineffective" for treating the symptoms of cancer and rheumatoid arthritis, the authors said.

The evidence was contradictory as to whether tai chi improved high blood pressure, type 2 diabetes, cardiovascular disease, muscle strength, osteoporosis and other conditions.

Many studies were flawed because they had a poor design or were at high risk of bias. For instance, they enrolled only small numbers of volunteers or lacked an adequate "control" group to ensure a fair comparison.

The overview was conducted by Myeong Soo Lee of the Korea Institute of Oriental Medicine in Daejeon, and Edzard Ernst of the University of Exeter, southwestern England.

It appeared in the British Journal of Sports Medicine, published by the British Medical Association (BMA).

Tai chi entails regular practice of deep breathing and relaxation techniques, combined with slow and gentle movements.

It is based on tenets in Confucian and Buddhist philosophies that there are two opposing life forces, yin and yang, which govern health.

Ill health results from an imbalance in these forces, but it can be corrected by tai chi, according to these beliefs.

- AFP/al



Taken from ChannelNewsAsia.com; source article is below:
Tai chi improves balance, mental health in elderly: study

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Face transplant man shows face

This is a second chance to life, and being more handsome than at first? Now that's a bonus!
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10 May 2011


Face transplant recipient Dallas Wiens (AFP Photo/ADAM HUNGER)
BOSTON, Massachusetts: A Texas man who burned his face off after his head touched an electrical wire while he was working in a cherry picker showed off his new look Monday as doctors presented the first US full face transplant.

Wearing black sunglasses and a dark goatee beard, 26-year-old Dallas Wiens appeared at a press conference alongside doctors who performed the operation at Brigham and Women's Hospital in the northeastern city of Boston.

"To me the face feels natural, as it if has become my own," said Wiens, acknowledging that he still feels numb in some places and needs to continue rehabilitation work to rebuild nerve function.

"I can never express what has been done, what I have been given," he added, thanking the donor family who wished to remain anonymous.

Wiens was injured in November 2008 when his head touched a high voltage electrical wire, causing dramatic facial deformities and burning off his nose and lips.

Plastic surgeon Bohdan Pomahac led the team of physicians, nurses and anesthesiologists for more than 15 hours to replace Wiens's nose, lips, facial skin, nerves and muscles.

The operation was done in March by a 30-strong team at Brigham and Women's Hospital, which said it was "the first full face transplant" performed in the country.

"He was quite literally a man without a face," said Pomahac.

The world's first full face transplant took place in Spain, and was unveiled in July 2010 by doctors at Vall d'Hebron hospital in Barcelona.

The 31-year-old recipient, identified only as Oscar, reportedly suffered injuries in a shooting accident and spoke at a televised news conference with considerable difficulty. He could not close his mouth and his face appeared swollen.

The first successful partial face transplant was performed in France in 2005 on Isabelle Dinoire, a 38-year-old woman who had been mauled by her dog.

Since then face transplants have been carried out in China, the United States and Spain, which carried out its first such operation in August 2009.

Wiens, who lost his eyesight in the accident, also spoke with some difficulty, but said he has already begun to regain his sense of smell.

"The ability to breathe through my nose normally, that in itself was a major gift," he said.

Now he is considering university education and is looking forward to leading a more normal life with his young daughter, who was enamoured by his new look.

"She actually said 'Daddy, you're so handsome,'" he said.

-AFP/wk



Taken from ChannelNewsAsia.com; source article is below:
Face transplant man makes appearance

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Taiwan doomsday prophet sparks panic

Montage of various Taipei imagesImage via WikipediaJust how easily can many be swayed... by fraudsters!
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1 May 2011

Police in Taiwan are investigating a self-proclaimed prophet whose doomsday warnings on a blog have caused panic.
The man, identifying himself as Teacher Wang, said Taiwan would be struck by a magnitude-14 earthquake and 170m (560ft) high tsunami on 11 May.
More than 100 cargo containers have been bought and set up in a mountainous area of central Taiwan.
Police said they were investigating if the blogger had conspired with a container business to defraud people.
"Teacher Wang" suggested people live in such containers to survive the disaster, which he said would kill millions of people and split the island in half.
'Hide my face'
Taiwan's famous Taipei 101 skyscraper and the Presidential Office building would be toppled, he warned.

More than 100 cargo containers have been discovered in the town of Puli, Nantou county.
Workers had been hired to fit them with doors, windows and air conditioning, says the BBC's Cindy Sui in Taipei.
The containers cost about $5,500 (£3,300) each, once water and electricity are included, our correspondent adds.
Taiwan is in a quake zone. In 1999 a 7.6-magnitude tremor killed more than 2,400 people and damaged 50,000 buildings.
But Taiwan's Central Weather Bureau says there is no basis for the doomsday prediction, since a magnitude-14 tremor is unheard of, and quakes cannot be reliably predicted.
Officials say Japan's recent devastating quake and tsunami may have led fraudsters to exploit people's fears.
The police have not been able to trace "Teacher Wang", who had touted his theory to TV reporters but insisted his face not be shown.
The authorities have removed his doomsday warnings from the internet.
Fraud convictions carry a maximum five-year jail term while breaking the law on social order is punishable by a fine of up to $1,000, said Taiwanese police.
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Taken from bbc.co.uk; source article is below:
Taiwan doomsday prophet's blog sparks panic

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Braces at 50?

Some things that you'd wish you have when going 50 and beyond.

I'm just thinking, will you wish for memory enhancer, and you are given pills to take, but you forget your medication altogether?

Oh well... as one shirt says, "enjoy getting old - not too many people get the privilege."
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By Eveline Gan, TODAY
Posted: 01 February 2011

Braces
SINGAPORE - When her 20-year-old daughter decided to get braces last year, Madam Tay J M accompanied her to the clinic. By the end of the orthodontic appointment, Mdm Tay decided that like her daughter, she wanted to get her teeth fixed too. Never mind that she was 52 years old.

"I like beautiful teeth. A nice set of teeth will help to boost my self-confidence," said Mdm Tay, who works as a secretary. "My teeth jut out slightly and they've yellowed over the years. At first I thought of only whitening them but I thought why not just go the whole way? Hopefully, I will have many more good years to go."

Mdm Tay now wears the Invisalign, a type of clear braces which are removable at mealtimes and during brushing.

At an age when some of her peers are already wearing dentures, Mdm Tay is rather self-conscious about her braces. This is why she opted for more "visually discreet" braces.

Orthodontic specialists, however, said patients like Mdm Tay are not a rarity. Once associated only with children and teens, braces are now becoming increasingly popular with adults seeking orthodontic treatment at a later age.

At I.Dental Surgeons, more than a third of those seeking orthodontic treatment are above the age of 30.

"It is not uncommon to see 40 to 50-year-olds straightening their teeth nowadays, compared to five years ago, when most of our patients were in their teens and early 20s," said dental surgeon Dr Cheng Eng Wah, principal partner and founder of I.Dental, who estimated the increase to be about 15 to 20 per cent in the past five years.

At Dr Cheng's clinic, adults like Mdm Tay tend to opt for "more aesthetically pleasing braces" such as Invisalign or ceramic braces with transparent brackets, rather than regular metal braces.

Depending on the individual's condition, the treatment costs with regular metal braces start from S$2,800 onwards, while treatment with Invisalign start from S$6,500 onwards.


Investing in the perfect smile

The trend is driven by people's "willingness to invest in aesthetics", as society becomes more affluent, Dr Cheng said.

"I think people are more aware of how a nice smile can improve their appearance and the way they present themselves. Beautiful teeth are part of what builds confidence, especially when interacting socially or professionally," he added.

Aesthetics aside, having a full set of straight teeth has its health benefits.

"For instance, properly aligned teeth have a lower risk of decay compared to 'overcrowded' teeth, as brushing and cleaning are easier with straight teeth," explained Dr Cheng.

Associate Professor Kelvin Foong, a senior consultant at the National University Hospital's department of preventive dentistry, said with the ageing population keeping their teeth longer, more complex rebuilding of the dentition could require braces to align the teeth before wearing prostheses such as crowns, implants and dentures.

At his clinic in NUH, Assoc Prof Foong's oldest patient was a 65-year-old who required minor tooth rearrangement using braces, before getting a new set of dentures.

While it is ideal to treat certain orthodontic conditions such as cross-bite and deviated jaw before the child reaches puberty, the experts said there isn't a "cut-off" age for getting braces. So you could be pushing 70 and still be able to get braces without harming your oral tissues.

Braces work by delivering light force to the crown of the tooth. The tooth moves to another position, when bone surrounding its root reorganises itself under pressure from the light force, explained Assoc Prof Foong.

"If a person's teeth are supported by healthy gums and bone, then it is possible to move teeth from one position to another within each jaw bone," he said.


Not for everyone

There are certain adults who are unsuitable for braces treatment.

Assoc Prof Foong cautioned those above the age of 40 who have untreated moderate to advanced gum disease, as well as medical conditions such as uncontrolled diabetes and heavy smokers against getting braces.

Those who take medications that affect the flow of saliva, such as high blood pressure medication, also should not get braces. He explained that having braces in a dry mouth gives rise to the risk of tooth decay.

Six months into her orthodontic treatment, Mdm Tay has become used to wearing braces.

"The first month was the most difficult but I could bear the pain quite well. Right now, I almost forget they are there in my mouth," she said, laughing.

Mdm Tay feels her trouble, effort and money will be well worth it in the end, when her braces finally come off and she can partake in celebrations with a bigger and brighter smile.

- TODAY/rl


Taken from ChannelNewsAsia.com; source article is below:
Braces at 50?



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